Isoflavonoids with antiestrogenic activity from Millettia pachycarpa

被引：45

作者：

Ito, C

Itoigawa, M ^{[1
]}

Kumagaya, M

Okamoto, Y

Ueda, K

Nishihara, T

Kojima, N

Furukawa, H

机构：

[1] Tokai Gakuen Univ, Fac Human Wellness, Tempa Ku, Nagoya, Aichi 4688514, Japan

[2] Meijo Univ, Fac Pharm, Dept Med Chem, Tempa Ku, Nagoya, Aichi 4688503, Japan

[3] Meijo Univ, Fac Pharm, Dept Hyg Chem, Tempa Ku, Nagoya, Aichi 4688503, Japan

[4] Osaka Univ, Ctr Adv Sci & Innovat, Suita, Osaka 5650871, Japan

来源：

JOURNAL OF NATURAL PRODUCTS | 2006年 / 69卷 / 01期

关键词：

D O I：

10.1021/np050341w

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Three new isoflavonoids, named millewanins G (1) and H (2) and furowanin B (3), were isolated from the leaves of Millettia pachycarpa. Their structures were elucidated on the basis of spectroscopic analyses. The antiestrogenic activity in the yeast two-hybrid assay of these isoflavonoids was examined and shown to be comparable with that of 4-hydroxytamoxifen.

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页码：138 / 141

页数：4

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