Copper-mediated C-H bond arylation of arenes with arylboronic acids

被引：140

作者：

Ban, Ikuya ^{[1
]}

Sudo, Tomoko ^{[1
]}

Taniguchi, Tadashi

Itami, Kenichiro ^{[1
,2
]}

机构：

[1] Nagoya Univ, Grad Sch Sci, Dept Chem, Nagoya, Aichi 4648602, Japan

[2] Japan Sci & Technol Agcy, PRESTO, Kanagawa, Japan

来源：

ORGANIC LETTERS | 2008年 / 10卷 / 16期

关键词：

D O I：

10.1021/ol8013717

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new copper-mediated cross-coupling of arenes and arylboronic acids is described. Under the influence of Cu(OCOCF3)(2), the C-H bond arylation of electron-rich arenes with arylboronic acids takes place to afford a range of biaryis in good yields. The reaction is selective for cross-coupling; no homocoupling product arising from arenes or arylboronic acids is detected. Multiple C-H bond arylation is possible with indoles and pyrroles furnishing interesting extended pi-systems.

引用

页码：3607 / 3609

页数：3

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