Effect of Mahonia aquifolium stem bark crude extract and one of its polysaccharide components on production of IL-8

被引：16

作者：

Kost'álová, D

Kardosová, A

Hajnická, V

机构：

[1] Comenius Univ, Fac Pharm, Dept Pharmacognosy & Bot, SK-82332 Bratislava 3, Slovakia

[2] Slovak Acad Sci, Inst Chem, SK-84238 Bratislava, Slovakia

[3] Inst Prevent & Clin Med, SK-83301 Bratislava, Slovakia

来源：

FITOTERAPIA | 2001年 / 72卷 / 07期

关键词：

Mahonia aquifolium; polysaccharides; interleukin-8; production; antipsoriatic effect;

D O I：

10.1016/S0367-326X(01)00336-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The crude hydroalcoholic extract of Mahonia aquifolium stem bark and a polysaccharide isolated from the extract were tested for their activity on interleukin-8 (IL-8) production by human monocytic cell line THP-1. The crude extract partly inhibited the IL-8 spontaneous production after 48-h treatment of the cells, while the polysaccharide was found to be a potent inducer of IL-8 production. (C) 2001 Elsevier Science B.V. All rights reserved.

引用

页码：802 / 806

页数：5

共 16 条

[1] Traditional medicine as a source of new therapeutic agents against psoriasis [J].