High rates of erythromycin and clindamycin resistance among OBGYN isolates of group B Streptococcus

被引:40
作者
DiPersio, LP
DiPersio, JR [1 ]
机构
[1] Dept Pathol & Lab Med, Summa Hlth Syst, Akron, OH 44304 USA
[2] Falor Div Surg Res, Summa Hlth Syst, Akron, OH 44304 USA
关键词
Streptococcus agalactiae; methylase genes; erythromycin;
D O I
10.1016/j.diagmicrobio.2005.07.003
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
In vitro susceptibility testing on 200 Streptococcus agalactiae strains isolated during a 4-year period from vaginal/rectal specimens demonstrated a very high resistance rate for both erythromycin (54%) and clindamycin (33%). Methylase genes erm(13) and erm(TR) and efflux genes mef(E) and mef(A) were detected. Pulsed-field gel electrophoresis showed evidence of both clonal spread and multiclonal dissemination of resistant strains. All but 3 of 200 isolates were susceptible to telithromycin. (c) 2006 Elsevier Inc. All rights reserved.
引用
收藏
页码:79 / 82
页数:4
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