Twins and virtual twins: bases of relative body weight revisited

被引：60

作者：

Segal, NL

Allison, DB

机构：

[1] Calif State Univ Fullerton, Dept Psychol, Fullerton, CA 92834 USA

[2] Calif State Univ Fullerton, Twin Studies Ctr, Fullerton, CA 92834 USA

[3] Univ Alabama Birmingham, Dept Biostat, Sect Stat Genet, Birmingham, AL 35294 USA

[4] Univ Alabama Birmingham, Clin Nutr Res Ctr, Birmingham, AL 35294 USA

来源：

INTERNATIONAL JOURNAL OF OBESITY | 2002年 / 26卷 / 04期

关键词：

twins; virtual twins; adoptees; body mass index; covariance structure analysis;

D O I：

10.1038/sj.ijo.0801941

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE: Application of a new investigative strategy to assess genetic and environmental influences on relative body weight. DESIGN: Covariance structure analysis of body mass index (BMI) using genetically informative samples. SUBJECTS: One-hundred and fourteen monozygotic (MZ) twin pairs (age 5.04-22.93y), 81 dizygotic (DZ) twin pairs (age 6.05 -16.52 y), and 98 virtual twin (VT) pairs, ie same-age unrelated siblings (3.68 -54.75 y). MEASUREMENTS: Height, weight, BMI variously obtained by direct measurement and self-report. RESULTS: In contrast with most previous studies, significant common environmental influence on BMI was observed. CONCLUSION: Much past research may have underestimated common environmental effects on BMI because the designs lacked the power or ability to detect them.

引用

页码：437 / 441

页数：5

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