Statistical mechanics of protein-like heteropolymers

被引：12

作者：

Dima, RI ^{[1
]}

Banavar, JR

Cieplak, M

Maritan, A

机构：

[1] Penn State Univ, Dept Phys, Davey Lab 104, University Pk, PA 16802 USA

[2] Penn State Univ, Ctr Phys Mat, University Pk, PA 16802 USA

[3] Polish Acad Sci, Inst Phys, PL-02668 Warsaw, Poland

[4] Ist Nazl Fis Nucl, Int Sch Adv Studies, SISSA, I-34014 Trieste, Italy

[5] Abdus Salam Int Ctr Theoret Phys, Trieste, Italy

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1999年 / 96卷 / 09期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1073/pnas.96.9.4904

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A strategy is outlined for obtaining the free energy of a typical designed heteropolymer. The design procedure considers the probability that the target conformation is occupied in comparison with all the other conformations that could house the given sequence, Numerical calculations on lattice heteropolymer models are presented to illustrate the key physical principles.

引用

页码：4904 / 4907

页数：4

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