Chemistry of the camptothecins in the bloodstream - Drug stabilization and optimization of activity

被引：48

作者：

Burke, TG

机构：

[1] LUCILLE P MARKEY CANC CTR, LEXINGTON, KY 40506 USA

[2] OHIO STATE UNIV, COLL PHARM, DIV PHARMACEUT, COLUMBUS, OH 43210 USA

来源：

CAMPTOTHECINS: FROM DISCOVERY TO THE PATIENT | 1996年 / 803卷

关键词：

D O I：

10.1111/j.1749-6632.1996.tb26373.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：29 / 31

页数：3

共 18 条

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MI, ZH ;

JIANG, Y .

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[2] LIPID BILAYER PARTITIONING AND STABILITY OF CAMPTOTHECIN DRUGS [J].

BURKE, TG ;

MISHRA, AK ;

WANI, MC ;

WALL, ME .

BIOCHEMISTRY, 1993, 32 (20) :5352-5364

[3] LIPOSOMAL STABILIZATION OF CAMPTOTHECINS LACTONE RING [J].

BURKE, TG ;

STAUBUS, AE ;

MISHRA, AK ;

MALAK, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (21) :8318-8319

[4] THE STRUCTURAL BASIS OF CAMPTOTHECIN INTERACTIONS WITH HUMAN SERUM-ALBUMIN - IMPACT ON DRUG STABILITY [J].

BURKE, TG ;

MI, ZH .

JOURNAL OF MEDICINAL CHEMISTRY, 1994, 37 (01) :40-46

[5] PREFERENTIAL BINDING OF THE CARBOXYLATE FORM OF CAMPTOTHECIN BY HUMAN SERUM-ALBUMIN [J].

BURKE, TG ;

MI, ZH .

ANALYTICAL BIOCHEMISTRY, 1993, 212 (01) :285-287

[6] STABILIZATION OF TOPOTECAN IN LOW PH LIPOSOMES COMPOSED OF DISTEAROYLPHOSPHATIDYLCHOLINE [J].

BURKE, TG ;

GAO, X .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1994, 83 (07) :967-969

[7] MODIFICATION OF THE HYDROXY LACTONE RING OF CAMPTOTHECIN - INHIBITION OF MAMMALIAN TOPOISOMERASE-I AND BIOLOGICAL-ACTIVITY [J].

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CARANFA, MJ ;

HOLDEN, KG ;

JAKAS, DR ;

GALLAGHER, G ;

MATTERN, MR ;

MONG, SM ;

BARTUS, JO ;

JOHNSON, RK ;

KINGSBURY, WD .

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[8]

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[9]

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[10]

MI Z, 1995, BIOCHEMISTRY-US, V35, P13722

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