Integrins and prostate cancer metastases

被引：94

作者：

Fornaro, M ^{[1
]}

Manes, T ^{[1
]}

Languino, LR ^{[1
]}

机构：

[1] Yale Univ, Sch Med, Dept Pathol, New Haven, CT 06520 USA

来源：

CANCER AND METASTASIS REVIEWS | 2001年 / 20卷 / 3-4期

关键词：

integrin; adhesion; migration; survival; proliferation; signaling;

D O I：

10.1023/A:1015547830323

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Integrins have emerged as modulators of a variety of cellular functions. They have been implicated in cell migration, survival, normal and aberrant cellular growth, differentiation, gene expression, and modulation of intracellular signal transduction pathways. In this review article, the structural and functional characteristics of integrins, their expression and their potential role in prostate cancer metastases will be discussed.

引用

页码：321 / 331

页数：11

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