A note on including time-dependent covariate in regression model for competing risks data

被引：43

作者：

Latouche, A ^{[1
]}

Porcher, R ^{[1
]}

Chevret, S ^{[1
]}

机构：

[1] Hop St Louis, APHP, INSERM, U717,Dept Biostat & Informat Med, F-75010 Paris, France

来源：

BIOMETRICAL JOURNAL | 2005年 / 47卷 / 06期

关键词：

time-dependent covariate; cumulative incidence; competing risk;

D O I：

10.1002/bimj.200410152

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Recently, regression analysis of the cumulative incidence function has gained interest in competing risks data analysis, through the model proposed by Fine and Gray (JASA 1999; 94: 496-509). In this note, we point out that inclusion of time-dependent covariates in this model can lead to serious bias. We illustrate the problems arising in such a context, using bone marrow transplant data as a working example and numerical simulations. Practical advices are given, preventing the misuse of this model.

引用

页码：807 / 814

页数：8

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