Demographic and Clinical Correlates of Diabetes-Related Quality of Life among Youth with Type 1 Diabetes

被引:97
作者
Lawrence, Jean M. [1 ]
Yi-Frazier, Joyce P. [2 ]
Black, Mary Helen [1 ]
Anderson, Andrea [3 ]
Hood, Korey [4 ]
Imperatore, Giuseppina [5 ]
Klingensmith, Georgeanna J. [6 ]
Naughton, Michelle [3 ]
Mayer-Davis, Elizabeth J. [7 ,8 ,9 ]
Seid, Michael [10 ,11 ]
机构
[1] Kaiser Permanente So Calif, Dept Res & Evaluat, Pasadena, CA 91101 USA
[2] Univ Washington, Sch Med, Dept Pediat, Seattle, WA 98195 USA
[3] Wake Forest Univ, Bowman Gray Sch Med, Dept Biostat Sci, Div Publ Hlth Sci, Winston Salem, NC USA
[4] Cincinnati Childrens Hosp Med Ctr, Ctr Promot Treatment Adherence & Self Management, Cincinnati, OH USA
[5] Ctr Dis Control & Prevent, Div Diabet Translat, Atlanta, GA USA
[6] Univ Colorado, Barbara Davis Ctr, Denver, CO 80202 USA
[7] Univ N Carolina, Gillings Sch Global Publ Hlth, Dept Nutr, Chapel Hill, NC USA
[8] Univ N Carolina, Dept Med, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA
[9] Univ N Carolina, Sch Med, Chapel Hill, NC USA
[10] Cincinnati Childrens Hosp Med Ctr, Div Pulm Med, Cincinnati, OH USA
[11] Cincinnati Childrens Hosp Med Ctr, James M Anderson Ctr Hlth Syst Excellence, Cincinnati, OH USA
关键词
METABOLIC-CONTROL; CHILDREN; ADOLESCENTS; SEARCH; DEPRESSION; PREVALENCE; OVERWEIGHT;
D O I
10.1016/j.jpeds.2012.01.016
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Objectives To evaluate the reliability and cluster structure of the Pediatric Quality of Life Inventory Type 1 Diabetes Module 3.0 (PedsQL-T1DM) and associated subscales and to explore the associations between PedsQL-T1DM total score and demographic and clinical characteristics and clinical indicators among a large racially/ethnically diverse cohort of youth with type 1 diabetes. Study design Principal components analysis was conducted on responses from the PedsQL-T1DM child self-report forms completed by SEARCH for Diabetes in Youth study participants aged >= 5 years. Multivariate linear regression models were fit to examine the associations among PedsQL-T1DM total score, demographic and clinical characteristics, and clinical indicators. Results The sample comprised 2602 youth with a mean age of 13.6 +/- 4.1 years and a mean T1DM duration of 62.1 +/- 47.0 months. Principal components analysis did not support the 5 existing PedsQL-T1DM subscales. In multivariate analyses, the PedsQL-T1DM total score was negatively and significantly associated with younger age (5-7 years), female sex, receiving insulin by injection (vs pump), having parents without a college degree, Medicaid/Medicare insurance, and having a comorbid medical condition. Youth with poor glycemic control based on their age-specific hemoglobin A1c target values and those with depressive symptoms had significantly lower PedsQL-T1DM scores than their counterparts with good control and no or limited depressive symptoms. Conclusion This study has identified sociodemographic and clinical characteristics of youth with T1DM more likely to experience poor diabetes-specific quality of life. The association of lower PedsQL-T1DM scores with depressive symptoms and poor glycemic control is especially concerning and may be the focus of future interventions and studies. (J Pediatr 2012;161:201-7).
引用
收藏
页码:201 / +
页数:9
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