Prevalence and characteristics of unilateral knee osteoarthritis in a community sample of elderly Japanese: do fractures around the knee affect the pathogenesis of unilateral knee osteoarthritis?

被引：22

作者：

Nishimura, Akinobu ^{[1
,2
]}

Hasegawa, Masahiro ^{[1
]}

Wakabayashi, Hiroki ^{[1
]}

Yoshida, Kakunoshin ^{[1
]}

Kato, Ko ^{[2
]}

Yamada, Tomomi ^{[3
]}

Uchida, Atsumasa ^{[1
]}

Sudo, Akihiro ^{[1
]}

机构：

[1] Mie Univ, Grad Sch Med, Dept Orthopaed Surg, Tsu, Mie 5148507, Japan

[2] Mie Univ, Grad Sch Med, Dept Orthopaed & Sports Med, Tsu, Mie 5148507, Japan

[3] Mie Univ, Grad Sch Med, Dept Translat Med Sci, Tsu, Mie 5148507, Japan

来源：

JOURNAL OF ORTHOPAEDIC SCIENCE | 2012年 / 17卷 / 05期

关键词：

BONE-MINERAL DENSITY; RISK-FACTORS; RADIOGRAPHIC OSTEOARTHRITIS; WOMEN; INJURY; OBESITY; ASSOCIATION; PROGRESSION; POPULATION; LIGAMENT;

D O I：

10.1007/s00776-012-0263-3

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

100224 [整形外科学];

摘要：

The purpose of this study was to investigate the prevalence and characteristics of unilateral knee osteoarthritis (KOA), to investigate what percent of contralateral healthy knees in patients with unilateral KOA progress to KOA, and to investigate whether knee fractures influence unilateral KOA. Studies were performed every two years from 1997 to 2009 in Miyagawa village, for a total of seven studies. A total of 1239 village inhabitants aged a parts per thousand yen65 years participated in these studies at least once. KOA was defined as a Kellgren-Lawrence (K/L) grade a parts per thousand yen2. Based on the knee X-ray at the first examination, participants were divided into three groups: no KOA (N group), unilateral KOA (U group), and bilateral KOA (B group). The U group was divided into two subgroups: K/L grade II-I combination (II-I group), and the U group without the II-I combination (G > 2 group). To investigate whether knee fractures influence unilateral KOA, the fracture history was considered. The percentages of participants classified into the N, B, and U groups (II-I and G > 2 group) were 68.4, 21.6, and 10.0 % (7.8 and 2.1 %), respectively. Most of the U group had the II-I combination (78.7 %). The percentages of knee fractures in the N, B, II-I, and G > 2 groups were 3.3, 5.3, 6.3, and 38.5 %, respectively. Overall, 49.2 % of the U group proceeded to bilateral KOA over an average of 5.3 years. The prevalences of definite radiographic bilateral and unilateral KOA were 21.6 and 10.0 %, respectively. Overall, 49.2 % of the participants with unilateral KOA developed KOA in the contralateral knee over an average of 5.3 years. If bilateral KOA advanced simultaneously, the II-I group was considered to represent the midpoint of progression to bilateral KOA. Bilateral KOA advanced simultaneously except in cases with a history of knee trauma, such as fractures.

引用

页码：556 / 561

页数：6

共 29 条

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