Polymorphonuclear leukocytes and innate immunity to Salmonella infections in mice

被引：31

作者：

Fierer, J

机构：

[1] VA San Diego Healthcare Syst, Dept Med, Infect Dis Sect 111F, La Jolla, CA 92161 USA

[2] VA San Diego Healthcare Syst, Dept Pathol, Infect Dis Sect 111F, La Jolla, CA 92161 USA

[3] Univ Calif San Diego, La Jolla, CA 92161 USA

来源：

MICROBES AND INFECTION | 2001年 / 3卷 / 14-15期

关键词：

neutrophils; Salmonella; phagocytosis;

D O I：

10.1016/S1286-4579(01)01483-6

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Neutropenia makes normal mice more susceptible to infection with spv (+) but not spv (-) Salmonella dublin. This shows the important role of polymorphonuclear leukocytes in resistance to Salmonella that can grow in host macrophages. Polymorphonuclear leukocytes, part of the innate immune system, kill Salmonella in a complement-dependent manner, and work in concert with macrophages. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

引用

收藏

页码：1233 / 1237

页数：5

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