Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography

被引：238

作者：

Goetzinger, Erich ^{[1
]}

Pircher, Michael ^{[1
]}

Geitzenauer, Wolfgang ^{[2
]}

Ahlers, Christian ^{[2
]}

Baumann, Bernhard ^{[1
]}

Michels, Stephan ^{[2
,3
]}

Schmidt-Erfurth, Ursula ^{[2
]}

Hitzenberger, Christoph K. ^{[1
]}

机构：

[1] Med Univ Vienna, Ctr Biomed Engn & Phys, Vienna, Austria

[2] Gen Hosp, Dept Ophthalmol, Vienna, Austria

[3] Univ Zurich Hosp, Dept Ophthalmol, Zurich, Switzerland

来源：

OPTICS EXPRESS | 2008年 / 16卷 / 21期

基金：

奥地利科学基金会;

关键词：

D O I：

10.1364/OE.16.016410

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We present a new method for identifying and segmenting the retinal pigment epithelium (RPE) in polarization sensitive optical coherence tomography (PS-OCT) images of the human retina. Contrary to previous, intensity based segmentation algorithms, our method uses an intrinsic tissue property of the RPE: its depolarizing, or polarization scrambling effect on backscattered light. Two different segmentation algorithms are presented and discussed: a simpler algorithm based on retardation data, and a more sophisticated algorithm based on local variations of the polarization state calculated from averaged Stokes vector elements. By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy and diseased eyes. (c) 2008 Optical Society of America

引用

页码：16410 / 16422

页数：13

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