Neonatal Infectious Diseases Evaluation of Neonatal Sepsis

被引:288
作者
Camacho-Gonzalez, Andres [1 ]
Spearman, Paul W. [1 ]
Stoll, Barbara J. [2 ]
机构
[1] Emory Univ, Childrens Healthcare Atlanta, Emory Dept Pediat, Div Pediat Infect Dis, Atlanta, GA 30322 USA
[2] Emory Childrens Ctr, Childrens Healthcare Atlanta Egleston, Dept Pediat, Atlanta, GA 30322 USA
关键词
Neonatal sepsis; Immature immunity; Early and late onset disease; Biologic markers; Treatment; INTENSIVE-CARE-UNIT; C-REACTIVE PROTEIN; EARLY-ONSET SEPSIS; STAPHYLOCOCCUS-AUREUS BACTEREMIA; EMPIRICAL ANTIBIOTIC-TREATMENT; TOTAL PARENTERAL-NUTRITION; ESCHERICHIA-COLI; NOSOCOMIAL INFECTIONS; PRETERM INFANTS; RISK-FACTORS;
D O I
10.1016/j.pcl.2012.12.003
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Neonatal sepsis remains a feared cause of morbidity and mortality in the neonatal period. Maternal, neonatal, and environmental factors are associated with risk of infection, and a combination of prevention strategies, judicious neonatal evaluation, and early initiation of therapy are required to prevent adverse outcomes. This article reviews recent trends in epidemiology and provides an update on risk factors, diagnostic methods, and management of neonatal sepsis.
引用
收藏
页码:367 / +
页数:24
相关论文
共 141 条
[1]   Antimicrobial resistance trends of Escherichia coli bloodstream isolates: a population-based study, 1998-2007 [J].
Al-Hasan, Majdi N. ;
Lahr, Brian D. ;
Eckel-Passow, Jeanette E. ;
Baddour, Larry M. .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2009, 64 (01) :169-174
[2]   Probiotics for prevention of necrotizing enterocolitis in preterm infants [J].
AlFaleh, K. ;
Bassler, D. .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2008, (01)
[3]   Prospective evaluation of a multi-factorial prevention strategy on the impact of nosocomial infection in very-low-birthweight infants [J].
Andersen, C ;
Hart, J ;
Vemgal, P ;
Harrison, C .
JOURNAL OF HOSPITAL INFECTION, 2005, 61 (02) :162-167
[4]  
[Anonymous], 2010, MMWR-MORBID MORTAL W
[5]   NEONATAL SEPSIS DUE TO GROUP-G STREPTOCOCCI [J].
APPELBAUM, PC ;
FRIEDMAN, Z ;
FAIRBROTHER, PF ;
HELLMANN, J ;
HALLGREN, EJ .
ACTA PAEDIATRICA SCANDINAVICA, 1980, 69 (04) :559-562
[6]   Serratia marcescens sepsis outbreak in a neonatal intensive care unit [J].
Arslan, Ugur ;
Erayman, Ibrahim ;
Kirdar, Sevin ;
Yuksekkaya, Serife ;
Cimen, Omer ;
Tuncer, Inci ;
Bozdogan, Buelent .
PEDIATRICS INTERNATIONAL, 2010, 52 (02) :208-212
[8]   Procalcitonin in detecting neonatal nosocomial sepsis [J].
Auriti, Cinzia ;
Fiscarelli, Ersilia ;
Ronchetti, Maria Paola ;
Argentieri, Marta ;
Marrocco, Gabriella ;
Quondamcarlo, Anna ;
Seganti, Giulio ;
Bagnoli, Francesco ;
Buonocore, Giuseppe ;
Serra, Giovanni ;
Bacolla, Gianfranco ;
Mastropasqua, Savino ;
Mari, Annibale ;
Corchia, Carlo ;
Prencipe, Giusi ;
Piersigilli, Fiammetta ;
Rava, Lucilla ;
Di Ciommo, Vincenzo .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2012, 97 (05) :F368-F370
[9]   Policy Statement-Recommendations for the Prevention of Perinatal Group B Streptococcal (GBS) Disease [J].
Baker, Carol J. ;
Byington, Carrie L. ;
Polin, Richard A. ;
Brady, Michael T. ;
Bernstein, Henry H. ;
Byington, Carrie L. ;
Edwards, Kathryn M. ;
Fisher, Margaret C. ;
Glode, Mary P. ;
Jackson, Mary Anne ;
Keyserling, Harry L. ;
Kimberlin, David W. ;
Maldonado, Yvonne A. ;
Orenstein, Walter A. ;
Schutze, Gordon E. ;
Willoughby, Rodney E. ;
Papile, Lu-Ann ;
Cummings, James ;
Baley, Jill E. ;
Bhutani, Vinod K. ;
Carlo, Waldemar A. ;
Kumar, Praveen ;
Polin, Richard A. ;
Tan, Rosemarie C. ;
Wang, Kasper S. ;
Watterberg, Kristi L. .
PEDIATRICS, 2011, 128 (03) :611-616
[10]   Neonatal Plasma Polarizes TLR4-Mediated Cytokine Responses towards Low IL-12p70 and High IL-10 Production via Distinct Factors [J].
Belderbos, Mirjam E. ;
Levy, Ofer ;
Stalpers, Femke ;
Kimpen, Jan L. ;
Meyaard, Linde ;
Bont, Louis .
PLOS ONE, 2012, 7 (03)