Stereoselective synthesis of axially chiral N-C bonds in N-aryl indoles

被引：64

作者：

Kamikawa, K ^{[1
]}

Kinoshita, S

Matsuzaka, H

Uemura, M

机构：

[1] Osaka Prefecture Univ, Grad Sch Sci, Dept Chem, Sakai, Osaka 5998531, Japan

[2] Kyoto Pharmaceut Univ, Yamashina, Kyoto 6408412, Japan

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 06期

关键词：

D O I：

10.1021/ol0529997

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-Aryl indoles with axially chiral N-C bonds were synthesized by stereoselective nucleophilic aromatic substitution reactions of planar chiral arene chromium complexes. Stereoselective chromium tricarbonyl migration was achieved in the sterically hindered N-aryl indole chromium complex by refluxing in toluene.

引用

页码：1097 / 1100

页数：4

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