Chiral furanoside phosphite-phosphoroamidites:: new ligands for asymmetric catalytic hydroformylation

被引：35

作者：

Diéguez, M ^{[1
]}

Ruiz, A ^{[1
]}

Claver, C ^{[1
]}

机构：

[1] Univ Rovira & Virgili, Dept Quim Fis & Inorgan, Tarragona 43005, Spain

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 20期

关键词：

D O I：

10.1016/S0957-4166(01)00489-X

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

We have designed a new series of phosphite phosphoroamidites ligands 1 4 based on a furanoside backbone. These ligands were screened in the Rh-catalyzed asymmetric hydroformylation of styrene, inducing high regioselectivities with 2-phenylpropanal md moderate enantioselectivities (up to 65%, c.e.). The results showed that the configuration of the stereogenic carbon atom C(3) at the ligand backbone had remarkable effects on the activity and enantioselectivity. Replacing the tert-butyl substituents with methoxy substituents at the para positions of the biphenyl moieties improved the enantioselectivities. We have also studied the solution structures of HRh(PP)(CO)(2) complexes. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：2827 / 2834

页数：8

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2-O

← 1 2 3 4 →