Total leucoderma: A rare manifestation of cutaneous chronic graft-versus-host disease

被引：20

作者：

Nagler, A

Goldenhersh, MA

LeviSchaffer, F

Bystryn, JC

Klaus, SN

机构：

[1] HADASSAH UNIV HOSP,DEPT DERMATOL,IL-91120 JERUSALEM,ISRAEL

[2] HADASSAH UNIV HOSP,DEPT PHARMACOL,IL-91120 JERUSALEM,ISRAEL

[3] HEBREW UNIV JERUSALEM,IL-91120 JERUSALEM,ISRAEL

[4] KAPLAN COMPREHENS CANC CTR,NEW YORK,NY

来源：

BRITISH JOURNAL OF DERMATOLOGY | 1996年 / 134卷 / 04期

关键词：

D O I：

10.1111/j.1365-2133.1996.tb06991.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 [皮肤病与性病学];

摘要：

We describe a 14-year-old boy who developed total leucoderma during the course of chronic graft-versus-host disease, which developed after allogeneic bone marrow transplantation. Skin biopsy and dihydroxy-phenylalanine staining revealed a total absence of melanocytes from the epidermis. Cytotoxic anti-melanocyte antibodies were found in the patient's serum, and this probably explains the development of the leucoderma.

引用

页码：780 / 783

页数：4

共 16 条

[1]

SCLERODERMATOUS CHRONIC GRAFT-VERSUS-HOST DISEASE - ANALYSIS OF 7 CASES [J].