Actinobacteria: A relevant minority for the maintenance of gut homeostasis

被引：749

作者：

Binda, Cecilia ^{[1
]}

Lopetuso, Loris Riccardo ^{[1
]}

Rizzatti, Gianenrico ^{[1
]}

Gibiino, Giulia ^{[1
]}

Cennamo, Vincenzo ^{[2
]}

Gasbarrini, Antonio ^{[1
]}

机构：

[1] Catholic Univ Sacred Heart Rome, A Gemelli Hosp, Dept Internal Med Gastroenterol & Hepatol, Rome, Italy

[2] AUSL Bologna Bellaria Maggiore Hosp, Unit Gastroenterol & Digest Endoscopy, Bologna, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2018年 / 50卷 / 05期

关键词：

Actinobacteria; Bifidobacteria spp; Dysbiosis; Gut homeostasis; Gut microbiota; Probiotic; IRRITABLE-BOWEL-SYNDROME; CHAIN FATTY-ACIDS; PROBIOTIC BIFIDOBACTERIUM-INFANTIS; ANTIBIOTIC-ASSOCIATED DIARRHEA; JAPANESE CEDAR POLLINOSIS; DOUBLE-BLIND; INTESTINAL MICROBIOTA; FECAL MICROFLORA; RESISTANT STARCH; ULCERATIVE-COLITIS;

D O I：

10.1016/j.dld.2018.02.012

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

100201 [内科学];

摘要：

Actinobacteria are one the four major phyla of the gut microbiota and, although they represent only a small percentage, are pivotal in the maintenance of gut homeostasis. During the last decade many studies focused the attention on Actinobacteria, especially on their role both in gastrointestinal and systemic diseases and on their possible therapeutic use. In fact, classes of this phylum, especially Bifidobacteria, are widely used as probiotic demonstrating beneficial effects in many pathological conditions, even if larger in vivo studies are needed to confirm such encouraging results. This review aims to explore the current knowledge on their physiological functions and to speculate on their possible therapeutic role(s) in gastrointestinal and systemic diseases. (C) 2018 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

引用

页码：421 / 428

页数：8

共 159 条

[1]

The role of the gut microbiota in nonalcoholic fatty liver disease [J].

Abu-Shanab, Ahmed ;

Quigley, Eamonn M. M. .

NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2010, 7 (12) :691-701

[2]

INTESTINAL COLONIZATION WITH ENTEROBACTERIACEAE IN PAKISTANI AND SWEDISH HOSPITAL-DELIVERED INFANTS [J].

ADLERBERTH, I ;

CARLSSON, B ;

DEMAN, P ;

JALIL, F ;

KHAN, SR ;

LARSSON, P ;

MELLANDER, L ;

SVANBORG, C ;

WOLD, AE ;

HANSON, LA .

ACTA PAEDIATRICA SCANDINAVICA, 1991, 80 (6-7) :602-610

[3]

Allen CA, 2008, ADV EXP MED BIOL, V635, P93, DOI 10.1007/978-0-387-09550-9_8

[4]

Enterotypes of the human gut microbiome [J].

Arumugam, Manimozhiyan ;

Raes, Jeroen ;

Pelletier, Eric ;

Le Paslier, Denis ;

Yamada, Takuji ;

Mende, Daniel R. ;

Fernandes, Gabriel R. ;

Tap, Julien ;

Bruls, Thomas ;

Batto, Jean-Michel ;

Bertalan, Marcelo ;

Borruel, Natalia ;

Casellas, Francesc ;

Fernandez, Leyden ;

Gautier, Laurent ;

Hansen, Torben ;

Hattori, Masahira ;

Hayashi, Tetsuya ;

Kleerebezem, Michiel ;

Kurokawa, Ken ;

Leclerc, Marion ;

Levenez, Florence ;

Manichanh, Chaysavanh ;

Nielsen, H. Bjorn ;

Nielsen, Trine ;

Pons, Nicolas ;

Poulain, Julie ;

Qin, Junjie ;

Sicheritz-Ponten, Thomas ;

Tims, Sebastian ;

Torrents, David ;

Ugarte, Edgardo ;

Zoetendal, Erwin G. ;

Wang, Jun ;

Guarner, Francisco ;

Pedersen, Oluf ;

de Vos, Willem M. ;

Brunak, Soren ;

Dore, Joel ;

Weissenbach, Jean ;

Ehrlich, S. Dusko ;

Bork, Peer .

NATURE, 2011, 473 (7346) :174-180

[5]

Luminal bacterial flora determines physiological expression of intestinal epithelial cytoprotective heat shock proteins 25 and 72 [J].

Arvans, DL ;

Vavricka, SR ;

Ren, HY ;

Musch, MW ;

Kang, L ;

Rocha, FG ;

Lucioni, A ;

Turner, JR ;

Alverdy, J ;

Chang, EB .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2005, 288 (04) :G696-G704

[6]

Ashida H, 2012, NATURE, V489, P231

[7]

Treg induction by a rationally selected mixture of Clostridia strains from the human microbiota [J].

Atarashi, Koji ;

Tanoue, Takeshi ;

Oshima, Kenshiro ;

Suda, Wataru ;

Nagano, Yuji ;

Nishikawa, Hiroyoshi ;

Fukuda, Shinji ;

Saito, Takuro ;

Narushima, Seiko ;

Hase, Koji ;

Kim, Sangwan ;

Fritz, Joelle V. ;

Wilmes, Paul ;

Ueha, Satoshi ;

Matsushima, Kouji ;

Ohno, Hiroshi ;

Olle, Bernat ;

Sakaguchi, Shimon ;

Taniguchi, Tadatsugu ;

Morita, Hidetoshi ;

Hattori, Masahira ;

Honda, Kenya .

NATURE, 2013, 500 (7461) :232-+

[8]

Coordinated regulation of the metabolome and lipidome at the host-microbial interface [J].

Backhed, Fredrik ;

Crawford, Peter A. .

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 2010, 1801 (03) :240-245

[9]

Prenatal stress alters bacterial colonization of the gut in infant monkeys [J].

Bailey, MT ;

Lubach, GR ;

Coe, CL .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2004, 38 (04) :414-421

[10]

Bailey MT, 1999, DEV PSYCHOBIOL, V35, P146, DOI 10.1002/(SICI)1098-2302(199909)35:2<146::AID-DEV7>3.0.CO

← 1 2 3 4 5 6 7 8 9 10 →