Management of multiple myeloma in Asia: resource-stratified guidelines

被引:49
作者
Tan, Daryl [1 ,2 ]
Chng, Wee Joo [3 ,4 ]
Chou, Takaaki [5 ]
Nawarawong, Weerasak [6 ]
Hwang, Shang-Yi [7 ]
Chim, Chor Sang [8 ]
Chen, Wenming [9 ]
Durie, Brian G. M. [10 ]
Lee, Jae Hoon [11 ]
机构
[1] Raffles Hosp, Raffles Canc Ctr, Singapore 88770, Singapore
[2] Singapore Gen Hosp, Dept Haematol, Singapore, Singapore
[3] Natl Univ Singapore, Canc Sci Inst Singapore, Singapore 117548, Singapore
[4] Natl Univ Hlth Syst, Inst Singapore, Natl Univ Canc, Dept Haematol Oncol, Singapore, Singapore
[5] Niigata Canc Ctr Hosp, Dept Internal Med, Niigata, Japan
[6] Chiang Mai Med Sch, Maung, Thailand
[7] Natl Taiwan Univ Hosp, Taipei, Taiwan
[8] Univ Hong Kong, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China
[9] Capital Med Univ, Beijing Chaoyang Hosp, Beijing, Peoples R China
[10] Cedars Sinai Comprehens Canc Ctr, Los Angeles, CA USA
[11] Gachon Univ, Gil Hosp, Inchon, South Korea
关键词
STEM-CELL TRANSPLANTATION; INTERNATIONAL STAGING SYSTEM; GROUP CONSENSUS STATEMENT; IN-SITU HYBRIDIZATION; HIGH-DOSE THERAPY; UNDETERMINED SIGNIFICANCE; MONOCLONAL GAMMOPATHY; RANDOMIZED-TRIAL; STANDARD CHEMOTHERAPY; PERIPHERAL NEUROPATHY;
D O I
10.1016/S1470-2045(13)70404-2
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Treatment of multiple myeloma has undergone substantial developments in the past 10 years. The introduction of novel drugs has changed the treatment of the disease and substantially improved survival outcomes. Clinical practice guidelines based on evidence have been developed to provide recommendations on standard treatment approaches. However, the guidelines do not take into account resource limitations encountered by developing countries. The huge disparities in economy, health-care infrastructure, and access to novel drugs in Asian countries hinder the delivery of optimum care to every patient with multiple myeloma in Asia. In this Review we outline the guidelines that correspond with different levels of health-care resources and expertise, with the aim to unify diagnostic and therapeutic guidelines and help with the design of future studies in Asia.
引用
收藏
页码:E571 / E581
页数:11
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