A powerful bronsted acid catalyst for the organocatalytic asymmetric transfer hydrogenation of imines

被引：547

作者：

Hoffmann, S ^{[1
]}

Seayad, AM ^{[1
]}

List, B ^{[1
]}

机构：

[1] Max Planck Inst Kohlenforsch, D-45470 Mulheim An Der Ruhr, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 45期

关键词：

asymmetric catalysis; chiral amines; rhomogeneous catalysis; hydrogenation; imines;

D O I：

10.1002/anie.200503062

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) A little goes a long way: A 1 mol % loading of the chiral phosphoric acid catalyst 2 converts aromatic and aliphatic imines such as 1 into the corresponding amines (4) in high yields and enantioselectivities if treated with Hantzsch dihydropyridine 3. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：7424 / 7427

页数：4

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