Fulminant hepatic failure associated with propylthiouracil: A case report with treatment emphasis on the use of plasmapheresis

被引：17

作者：

Aydemir, S ^{[1
]}

Ustundag, Y

Bayraktaroglu, T

Tekin, IO

Peksoy, I

Unal, AU

机构：

[1] Zonguldak Karaelmas Univ, Fac Med, Dept Gastroenterol, TR-67800 Zonguldak, Turkey

[2] Zonguldak Karaelmas Univ, Fac Med, Dept Internal Med, TR-67800 Zonguldak, Turkey

[3] Zonguldak Karaelmas Univ, Fac Med, Dept Immunol, TR-67800 Zonguldak, Turkey

[4] Zonguldak Karaelmas Univ, Fac Med, Dept Nucl Med, TR-67800 Zonguldak, Turkey

[5] Zonguldak Karaelmas Univ, Fac Med, Dept Neurol, TR-67800 Zonguldak, Turkey

来源：

JOURNAL OF CLINICAL APHERESIS | 2005年 / 20卷 / 04期

关键词：

propylthiouracil; hyperthyroidism; fulminant hepatic failure; plasmapheresis;

D O I：

10.1002/jca.20063

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Propylthiouracil is a commonly used medication for hyperthyroidism. Though propylthiouracil-induced hepatotoxicity is a rarely encountered problem, death due to fulminant hepatic failure may occur. In the English literature, only 34 cases have been described with severe hepatotoxicity secondary to this drug. Here We report a case of fulminant hepatic failure due to propylthiouracil and review the issues of treatment and management with special emphasis on the use of plasmapheresis in such situations.

引用

页码：235 / 238

页数：4

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