Asymmetric dihydroxylation of allenes

被引：25

作者：

Fleming, SA

Carroll, SM

Hirschi, J

Liu, RM

Pace, JL

Redd, JT

机构：

[1] Brigham Young Univ, Dept Chem & Biochem, Provo, UT 84602 USA

[2] So Utah Univ, Dept Chem & Biochem, Cedar City, UT 84720 USA

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 17期

关键词：

alpha-hydroxy ketones;

D O I：

10.1016/j.tetlet.2004.03.037

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have used asymmetric dihydroxylation (AD) of allenes in order to synthesize chiral of-hydroxy ketones. This methodology has been applied to several aryl-substituted allenes. We have found that electron donating groups on the aromatic ring increase the efficiency of the reaction. (C) 2004 Elsevier Ltd. All rights reserved.

引用

收藏

页码：3341 / 3343

页数：3

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