Can computers help to explain biology?

被引：34

作者：

Brent, R ^{[1
]}

Bruck, J

机构：

[1] Inst Mol Sci, Berkeley, CA 94704 USA

[2] CALTECH, Pasadena, CA 91125 USA

来源：

NATURE | 2006年 / 440卷 / 7083期

关键词：

D O I：

10.1038/440416a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The road leading from computer formalisms to explaining biological function will be difficult, but Roger Brent and Jehoshua Bruck suggest three hopeful paths that could take us closer to this goal.

引用

页码：416 / 417

页数：2

共 11 条

[1]

[Anonymous], 1964, MATH THEORY COMMUNIC

[2] Genomic biology [J].

Brent, R .

CELL, 2000, 100 (01) :169-183

[3] A network-based analysis of systemic inflammation in humans [J].

Calvano, SE ;

Xiao, WZ ;

Richards, DR ;

Felciano, RM ;

Baker, HV ;

Cho, RJ ;

Chen, RO ;

Brownstein, BH ;

Cobb, JP ;

Tschoeke, SK ;

Miller-Graziano, C ;

Moldawer, LL ;

Mindrinos, MN ;

Davis, RW ;

Tompkins, RG ;

Lowry, SF .

NATURE, 2005, 437 (7061) :1032-1037

[4] The future is function [J].

Fields, S .

NATURE GENETICS, 1997, 15 (04) :325-327

[5] EXACT STOCHASTIC SIMULATION OF COUPLED CHEMICAL-REACTIONS [J].

GILLESPIE, DT .

JOURNAL OF PHYSICAL CHEMISTRY, 1977, 81 (25) :2340-2361

[6] A RIGOROUS DERIVATION OF THE CHEMICAL MASTER EQUATION [J].

GILLESPIE, DT .

PHYSICA A, 1992, 188 (1-3) :404-425

[7] A QUANTITATIVE DESCRIPTION OF MEMBRANE CURRENT AND ITS APPLICATION TO CONDUCTION AND EXCITATION IN NERVE [J].

HODGKIN, AL ;

HUXLEY, AF .

JOURNAL OF PHYSIOLOGY-LONDON, 1952, 117 (04) :500-544

[8] The meaning of systems biology [J].

Kirschner, MW .

CELL, 2005, 121 (04) :503-504

[9]

Simon HA, 2019, The sciences of the artificial, Vthird

[10]

SUSSMAN GJ, 2001, NCR CSTB S FUND COMP

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