Alzheimer's disease research enters a "new cycle": How significant?

被引：19

作者：

Copani, A

Sortino, MA

Nicoletti, F

Stella, AMG

机构：

[1] Univ Catania, Dept Pharmaceut Sci, Sect Pharmacol, I-95125 Catania, Italy

[2] Univ Catania, Dept Expt & Clin Pharmacol, I-95125 Catania, Italy

[3] Univ Catania, Dept Chem Sci, Sect Biochem & Mol Biol, I-95125 Catania, Italy

来源：

NEUROCHEMICAL RESEARCH | 2002年 / 27卷 / 1-2期

关键词：

cell cycle; neuronal apoptosis; beta-amyloid protein; Alzheimer's disease;

D O I：

10.1023/A:1014879311761

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent evidence suggests a link between the aberrant re-expression of cell cycle proteins in adult neurons of the Alzheimer's disease brain and the process of apoptotic degeneration, Here we will discuss this unexpected phenomenon as related to the mechanisms of beta-amyloid toxicity, and its significance for therapeutic possibilities.

引用

收藏

页码：173 / 176

页数：4

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