A PCR-RFLP typing method for adhesion molecule gene polymorphisms and allele frequencies in a normal UK population

被引：13

作者：

Gbadegesin, RA

Watson, CJ

Cotton, SA

Brenchley, PEC

Webb, NJA ^{[1
]}

机构：

[1] Royal Manchester Childrens Hosp, Dept Nephrol, Manchester M27 4HA, Lancs, England

[2] Manchester Royal Infirm, Manchester Inst Nephrol & Transplantat, Renal Res Labs, Manchester M13 9WL, Lancs, England

来源：

EUROPEAN JOURNAL OF IMMUNOGENETICS | 2002年 / 29卷 / 02期

关键词：

D O I：

10.1046/j.1365-2370.2002.00277.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

We report simple and reproducible PCR-RFLP typing methods for the polymorphisms in the ICAM-1, E-selectin and PECAM-1 genes. The genotype and allele frequencies detected in a normal UK population did not deviate significantly from the Hardy-Weinberg equilibrium; neither did they differ from frequencies previously reported. using SSP or SSCP methods.

引用

页码：109 / 111

页数：3

共 9 条

[1] LEUKOCYTE-ENDOTHELIAL INTERACTIONS AND REGULATION OF LEUKOCYTE MIGRATION [J].