Two new coumarin glycosides from Herpetospermum caudigerum

被引：28

作者：

Xu, Bing ^{[1
]}

Liu, Shuang ^{[1
]}

Fan, Xu-Dong ^{[1
]}

Deng, Li-Qing ^{[1
]}

Ma, Wen-Hui ^{[2
]}

Chen, Min ^{[1
]}

机构：

[1] Southwest Univ, Coll Pharmaceut Sci, Key Lab Luminescent & Real Time Analyt Chem, Minist Educ, Chongqing 400715, Peoples R China

[2] Shanghai Micronmr Informat Technol Co Ltd, Shanghai 200437, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2015年 / 17卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Herpetospermum caudigerum; coumarin glycoside; herpetosperin A; herpetosperin B; WALL;

D O I：

10.1080/10286020.2014.996137

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Phytochemical investigation on the seeds of Herpetospermum caudigerum afforded two new coumarin glycosides A and B (1 and 2), together with a known compound herpetolide A (3). Their structures were determined by spectroscopic methods, including 2D NMR techniques. Compound 3 exhibited cytotoxicity against HepG2 cells with IC50 value of 6.47g/ml. Compound 2 showed anti-hepatitis B virus activity with HBsAg secretion by 33.1% at 200g/ml.

引用

页码：738 / 743

页数：6

共 15 条

[1]

Neglschisandrins E-F: Two New Lignans and Related Cytotoxic Lignans from Schisandra neglecta [J].