Liquor made quicker: alcohol as a synthetic reagent for molecules in anesthesia

被引:5
作者
Fragoza, Keith [1 ]
Alston, Theodore A. [1 ]
机构
[1] Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Anesthesia & Crit Care, Boston, MA 02114 USA
关键词
Claude Bernard; Alfred Einhorn; Emil Fischer; Isabella Herb; Albert Hofmann; August Kekule; Charles Richet; Eduard Ritsert;
D O I
10.1016/j.jclinane.2008.07.002
中图分类号
R614 [麻醉学];
学科分类号
100217 [麻醉学];
摘要
Ethanol was an early anesthetic, and chemists transformed it into better ones. Hypnotic/anesthetic/analgesic molecules prepared from ethanol include barbiturates, benzocaine, chloral hydrate, chloroform, diethyl ether, ethyl chloride, ethylene, etomidate, meperidine, paraldehyde, phenacetin, procaine, tribromoethanol, and urethane. Ethanol was sometimes mixed deliberately with the other anesthetics, and John Snows inhaled amylene came from the fusel oil fraction of rotgut whisky. (C) 2008 Elsevier Inc. All rights reserved.
引用
收藏
页码:556 / 559
页数:4
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