Exposing culprit organic pollutants: A review

被引:60
作者
Keane, A
Phoenix, P
Ghoshal, S
Lau, PCK
机构
[1] Natl Res Council Canada, Biotechnol Res Inst, Montreal, PQ H4P 2R2, Canada
[2] McGill Univ, Dept Civil Engn & Appl Mech, Montreal, PQ H3A 2K6, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
biosensor; chemicals; bioluminescence; reporter genes; aromatic hydrocarbons; environmental biotechnology; bioavailability; bioremediation; gene regulation; groundwater pollution;
D O I
10.1016/S0167-7012(01)00382-7
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
There is a continuing need for monitoring the health of the environment due to the presence of pollutants. Here, we review the development and attributes of biosensors by which bacteria have been genetically modified to express the luminescence genes, i.e. to glove, in a quantified manner, in response to pollutants. we have concentrated on the detection of organic hydrocarbon pollutants and discussed the molecular mechanisms by which some of these chemicals act as effector molecules on the respective regulatory systems. The future of environmental biosensors is predictably bright. As more knowledge is gathered on the sensing regulatory component, the possibility of developing targeted or pollutant-specific biosensors is promising. Moreover, the repertoire of biosensors for culprit organic pollutants is expected to be enlarged through advances in genomics technology and identification of new sensory or receptor molecules. The need for pollutant detection at concentrations in the parts per trillion range or biosensors configured in a nanoscale is anticipated. Crown Copyright (C) 2002 Published by Elsevier Science B.V. All rights reserved.
引用
收藏
页码:103 / 119
页数:17
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