Epithermal neutron activation analysis of blue-green algae Spirulina platensis as a matrix for selenium-containing pharmaceuticals

被引:33
作者
Mosulishvili, LM [1 ]
Kirkesali, YI
Belokobylsky, AI
Khizanishvili, AI
Frontasyeva, MV
Gundorina, SF
Oprea, CD
机构
[1] Georgian Acad Sci, E L Andronikashvili Inst Phys, GE-380060 Tbilisi, Georgia
[2] Joint Inst Nucl Res, Dept Activat Anal & Radiat Res, Frank Lab Neutron Phys, Dubna 141980, Moscow Region, Russia
关键词
D O I
10.1023/A:1015219300665
中图分类号
O65 [分析化学];
学科分类号
070302 [分析化学]; 081704 [应用化学];
摘要
To evaluate the potentiality of the blue-green algae Spirulina platensis as a matrix for the production of Se-containing pharmaceuticals, the background levels of 31 major, minor and trace elements (Na, Mg, Al, Cl, K, Ca. Sc, V, Cr, Mn, Fe, Co, Ni using (n,p) reaction), As. Br, Zn, Rb, Mo, Ag, Sb, L, Ba, Sm, Th, Tm, Hf, Ta, W, Au, Hg, Th were determined in Spirulina platensis biomass by means of epithermal neutron activation analysis. The possibility of the purpose-oriented incorporation of Se into Spirulina platensis biomass was demonstrated. The polynomial dependence of the Se accumulation on nutritional medium loading was revealed. The analytical technique used allows to control the a-mount of toxic elements in algae Spirulina platensis. Based on this study, a conclusion of the possibility to use Spirulina platensis as a matrix for the production of Se-containing pharmaceutical was drawn.
引用
收藏
页码:15 / 20
页数:6
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