A score that verifies adherence to a gluten-free diet: a cross-sectional, multicentre validation in real clinical life

被引：107

作者：

Biagi, Federico ^{[1
]}

Bianchi, Paola Ilaria ^{[1
]}

Marchese, Alessandra ^{[1
]}

Trotta, Lucia ^{[1
]}

Vattiato, Claudia ^{[1
]}

Balduzzi, Davide ^{[1
]}

Brusco, Giovanna ^{[2
]}

Andrealli, Alida ^{[3
]}

Cisaro, Fabio ^{[3
]}

Astegiano, Marco ^{[3
]}

Pellegrino, Salvatore ^{[4
]}

Magazzu, Giuseppe ^{[4
]}

Klersy, Catherine ^{[5
]}

Corazza, Gino Roberto ^{[1
]}

机构：

[1] Univ Pavia, Coeliac Ctr, Dept Internal Med 1, Fdn IRCCS Policlin San Matteo, I-27100 Pavia, Italy

[2] Osped Civile Voghera, Internal Med Unit, Voghera, Italy

[3] Univ Turin, Dept Gastrohepatol, AOU San Giovanni Battista Molinette, I-10126 Turin, Italy

[4] Univ Messina, Reg Ctr Celiac Dis, Messina, Italy

[5] Fdn IRCCS Policlin San Matteo, Serv Biometry & Clin Epidemiol, Pavia, Italy

来源：

BRITISH JOURNAL OF NUTRITION | 2012年 / 108卷 / 10期

关键词：

Coeliac disease; Gliadin; Endomysial antibodies; Villous atrophy; CELIAC-DISEASE; MUCOSAL RECOVERY; MALIGNANCY; ANTIBODIES; ADULTS;

D O I：

10.1017/S0007114511007367

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

A dietary interview performed by expert personnel is the best method to check whether patients with coeliac disease follow a strict gluten-free diet (GFD). We previously developed a score based on four fast and simple questions that can be administered even by non-expert personnel. The aim of the present study is to verify the reliability of our questionnaire in a new cohort of patients. The questionnaire has a five-level score. From March 2008 to January 2011, the questionnaire was administered to 141 coeliac patients on a GFD, who were undergoing re-evaluation. The score obtained was compared with persistence of both villous atrophy and endomysial antibodies (EMA). The rate of lower scores was higher among the patients with persistence of either villous atrophy (Fisher's exact, P<0.001; test for trend, P<0.001) or positive EMA (Fisher's exact, P=0.001; test for trend, P=0.018). Given that the coeliac patients have been well instructed on what a GFD means and on how to follow it, our questionnaire is a reliable and simple method to verify compliance to a GFD.

引用

页码：1884 / 1888

页数：5

共 18 条

[1]

Biagi F, 2004, NUTR REV, V62, P360, DOI 10.1111/j.1753-4887.2004.tb00062.x

[2]

Endomysial and tissue transglutaminase antibodies in coeliac sera: a comparison not influenced by previous serological testing [J].