Fouling and non-fouling surfaces produced by plasma polymerization of ethylene oxide monomer

被引：99

作者：

Brétagnol, F ^{[1
]}

Lejeune, M ^{[1
]}

Papadopoulou-Bouraoui, A ^{[1
]}

Hasiwa, M ^{[1
]}

Rauscher, H ^{[1
]}

Ceccone, G ^{[1
]}

Colpo, P ^{[1
]}

Rossi, F ^{[1
]}

机构：

[1] Commiss European Communities, Joint Res Ctr, Inst Hlth & Consumer Protect, I-21020 Ispra, Italy

来源：

ACTA BIOMATERIALIA | 2006年 / 2卷 / 02期

关键词：

plasma polymerization; fouling and non-fouling coatings; protein and cell adhesion;

D O I：

10.1016/j.actbio.2005.11.002

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This paper presents the results of plasma polymerization using diethylene glycol dimethyl ether as a precursor in a capacitively coupled radio frequency system. The chemical structure of the coatings was characterized using several analysis techniques (X-ray photoelectron spectroscopy, Fourier transform-infrared spectroscopy, ellipsometry), while the biological response of these coatings has been tested by protein adsorption and cell culture experiments. The modulation of the input plasma power controls the concentration of polyethylene oxide groups in the coatings and allows the production of films with opposite protein and cell repellent properties. The study of the stability of these coatings in different media (water, acetone, phosphate-buffered saline) reveals that these films could be involved in classical lift-off processes for the production of patterned surfaces. (c) 2005 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved.

引用

页码：165 / 172

页数：8

共 33 条

[1] Biological responses to materials [J].

Anderson, JM .

ANNUAL REVIEW OF MATERIALS RESEARCH, 2001, 31 :81-110

[2]

Androde JD, 1985, SURFACE INTERFACIAL, P1

[3]

BATHIA SN, 2000, Patent No. 6133030

[4] Exploiting the current paradigm of blood-material interactions for the rational design of blood-compatible materials [J].

Brash, JL .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2000, 11 (11) :1135-1146

[5] Protein repellant silicone surfaces by covalent immobilization of poly(ethylene oxide) [J].

Chen, H ;

Zhang, Z ;

Chen, Y ;

Brook, MA ;

Sheardown, H .

BIOMATERIALS, 2005, 26 (15) :2391-2399

[6] Tissue engineering: the biophysical background [J].

Curtis, A ;

Riehle, M .

PHYSICS IN MEDICINE AND BIOLOGY, 2001, 46 (04) :R47-R65

[7] POLYMERIC MICROSPHERES AS DRUG CARRIERS [J].

DAVIS, SS ;

ILLUM, L .

BIOMATERIALS, 1988, 9 (01) :111-115

[8]

Goessl A, 2001, J BIOMED MATER RES, V57, P15, DOI 10.1002/1097-4636(200110)57:1<15::AID-JBM1136>3.0.CO

[9]

2-N

[10]

GRAHAM NB, 1984, BIOMATERIALS, V5, P27, DOI 10.1016/0142-9612(84)90063-2

← 1 2 3 4 →