Predominance and Circulation of Enteric Viruses in the Region of Greater Cairo, Egypt

被引:87
作者
Kamel, Aziza H. [2 ]
Ali, Mohamed A. [2 ]
El-Nady, Hala G. [3 ]
de Rougemont, Alexis
Pothier, Pierre [1 ]
Belliot, Gael
机构
[1] Publ Hosp Dijon, CHU Dijon, Virol Lab, Natl Reference Ctr Enter Viruses, F-21070 Dijon, France
[2] Natl Res Ctr, Dept Water Pollut Res, Virol Lab, Cairo 12311, Egypt
[3] Natl Res Ctr, Div Med, Dept Child Hlth, Cairo 12311, Egypt
关键词
NORWALK-LIKE VIRUSES; ROTAVIRUS DIARRHEA; NOROVIRUS; GASTROENTERITIS; IDENTIFICATION; EMERGENCE; CHILDREN; STRAIN; EPIDEMIOLOGY; OUTBREAKS;
D O I
10.1128/JCM.01381-08
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The circulation of enteric viruses among the population of Cairo, Egypt, between March 2006 and February 2007 was studied. At least one virus was detected in 50% of fecal samples, 57.4% of which were positive for rotavirus, 26% for norovirus, 10.4% for adenovirus, and 1.7% for astrovirus. Over 10% of infections were mixed infections. Rotavirus typing showed that G1P[8] and G2P[4] were predominant but that the unusual G12P[4] and G12P[6] reassortants were also present. Among the noroviruses, half belonged to the predominant GGII.4 cluster. The phylogenetic analysis of the capsid gene suggested that GGII.4 strains from Cairo were similar to those circulating elsewhere. It also showed the emergence of new GGII.4 variants that were not associated with any previously known GGII.4 isolate. Further studies are required to assess the disease burden of enteric viruses in Egypt and the impact of atypical strains.
引用
收藏
页码:1037 / 1045
页数:9
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