Ca2+-binding S100 proteins in the central nervous system

被引：122

作者：

Heizmann, CW ^{[1
]}

机构：

[1] Univ Zurich, Dept Pediat, Div Clin Chem & Biochem, CH-8032 Zurich, Switzerland

来源：

NEUROCHEMICAL RESEARCH | 1999年 / 24卷 / 09期

关键词：

calcium-binding proteins; Zn2+; neurodegenerative disorders; S100; proteins;

D O I：

10.1023/A:1020700117665

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A number of neurodegenerative disorders have been attributed to abberrations of intracellular Ca2+ homeostasis regulated by Ca2+-binding proteins. This chapter will focus on the S100B and S100A6 proteins, which are highly expressed in the central nervous system. Their protein structures, localizations, and association with brain pathology as well as their potential use in clinical diagnostics will be discussed.

引用

页码：1097 / 1100

页数：4

共 31 条

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