Localization of a 25 kDa human sperm surface protein: Its role in in-vitro human sperm capacitation

被引：16

作者：

Banerjee, M ^{[1
]}

Chowdhury, M ^{[1
]}

机构：

[1] INDIAN INST CHEM BIOL,CALCUTTA 700032,W BENGAL,INDIA

来源：

MOLECULAR HUMAN REPRODUCTION | 1997年 / 3卷 / 02期

关键词：

human sperm capacitation; mannose receptor; SABP; sialoglycoconjugates; superoxide anion;

D O I：

10.1093/molehr/3.2.109

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A human endometrial sialic acid-binding glycoprotein (SABP) binds specifically to a 25 kDa protein on the plasma membranes of human non-capacitated sperm heads. In-vitro labelling of the sperm surface sialoglycoconjugates and subsequent incubation with SABP, suggests removal of some sialoglycoconjugate moieties from the sperm surface upon interaction with SABP. SABP also induces the exposure of mannose ligand receptors on the sperm surface and increases the production of superoxide anion (O-2(.-)).

引用

页码：109 / 114

页数：6

共 30 条

[1] Induction of capacitation in human spermatozoa in vitro by an endometrial sialic acid-binding protein [J].