Topogenesis of inner membrane proteins of mitochondria

被引：64

作者：

Stuart, RA

Neupert, W

机构：

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1996年 / 21卷 / 07期

关键词：

D O I：

10.1016/0968-0004(96)10035-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Proteins of the inner mitochondrial membrane display a diverse range of topological arrangements. These proteins, encoded either by the nuclear or mitochondrial genomes, contain sequence determinants, so-called topogenic signals, which direct newly synthesized proteins to their final orientation in the membrane. The recent analysis of sorting pathways of a number of proteins highlights that these topogenic signals might act in different ways.

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页码：261 / 267

页数：7

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