Antibacterial effect of garlic and omeprazole on Helicobacter pylori

被引：72

作者：

Jonkers, D

van den Broek, E

van Dooren, I

Thijs, C

Dorant, E

Hageman, G

Stobberingh, E

机构：

[1] Univ Hosp Maastricht, Dept Med Microbiol, NL-6202 AZ Maastricht, Netherlands

[2] Univ Maastricht, Dept Epidemiol, Maastricht, Netherlands

[3] Univ Maastricht, Dept Hlth Risk Anal & Toxicol, Maastricht, Netherlands

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1999年 / 43卷 / 06期

关键词：

D O I：

10.1093/jac/43.6.837

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The antibacterial effect of a home-made raw garlic extract and commercial garlic tablets alone and in combination with antibiotics or omeprazole was determined against clinical isolates of Helicobacter pylori MIC values of raw garlic extract and three types of commercial garlic tablets ranged from 10,000 to 17,500 mg/L. When MIC values of the commercial tablets were based on the allicin content, no differences between the three types were observed. The combination of garlic and omeprazole, studied with killing curves, showed a synergic effect which was concentration dependent. Further clinical evaluation of garlic in combination with the conventional agents for H. pylori treatment seems warranted.

引用

页码：837 / 839

页数：3

共 10 条

[1] Inhibition of Helicobacter pylori by garlic extract (Allium sativum) [J].