Vibrational study of a nucleoside analogue with antiviral activity, 5-chloro-2′-deoxyuridine, CDU.

被引:1
作者
Bailey, L [1 ]
Navarro, R [1 ]
Hernanz, A [1 ]
机构
[1] Univ Nacl Educ Distancia, Dept Ciencias & Tecn Fis Quim, Madrid 28040, Spain
关键词
D O I
10.1080/15257779908041648
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The experimental FTIR and FT-Raman spectra of 5-chloro-2'-deoxyuridine have been assigned on the basis of normal coordinate analyses, in the light of observed and calculated wavenumbers and isotopic shifts. The results indicate that virtually all normal modes of IDU involve some degree of vibrational coupling between the chlorouracil base and the deoxyribose moiety.
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收藏
页码:1069 / 1071
页数:3
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