Blood Cells Need Glia, Too: A New Role for the Nervous System in the Bone Marrow Niche

被引：18

作者：

Brueckner, Katja ^{[1
]}

机构：

[1] Univ Calif San Francisco, Dept Anat, Dept Cell & Tissue Biol, Eli & Edythe Broad Ctr Regenerat Med & Stem Cell, San Francisco, CA 94143 USA

来源：

CELL STEM CELL | 2011年 / 9卷 / 06期

关键词：

STEM-CELLS; HIBERNATION;

D O I：

10.1016/j.stem.2011.11.016

中图分类号：

Q813 [细胞工程];

学科分类号：

100113 [医学细胞生物学];

摘要：

Regulation of hematopoietic stem cell (HSC) dormancy by specific cell types in the hematopoietic niche remains poorly understood. Yamazaki et al. (2011) now report that nerve-associated nonmyelinating Schwann cells activate TGF-beta to maintain dormant HSCs, suggesting that glia are novel players in the bone marrow niche.

引用

页码：493 / 495

页数：3

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