DNA replication: Stable driving prevents fatal smashes

被引：12

作者：

Donaldson, AD ^{[1
]}

Blow, JJ ^{[1
]}

机构：

[1] Univ Dundee, Sch Life Sci, CRC,Chromosome Replicat Res Grp, Div Gene Regulat & Express, Dundee DD1 5EH, Scotland

来源：

CURRENT BIOLOGY | 2001年 / 11卷 / 23期

关键词：

D O I：

10.1016/S0960-9822(01)00579-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cells respond to DNA damage during S phase by slowing chromosome replication. Recent results have shed light on the mechanism by which this 'intra-S phase' checkpoint is implemented.

引用

页码：R979 / R982

页数：4

共 15 条

[1] THE LOCALIZATION OF REPLICATION ORIGINS ON ARS PLASMIDS IN SACCHAROMYCES-CEREVISIAE
BREWER, BJ
FANGMAN, WL
[J]. CELL, 1987, 51 (03) : 463 - 471
[2] The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast
Brush, GS
Morrow, DM
Hieter, P
Kelly, TJ
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (26) : 15075 - 15080
[3] Inhibition of initiation of simian virus 40 DNA replication in infected BSC-1 cells by the DNA alkylating drug adozelesin
Cobuzzi, RJ
Burhans, WC
Beerman, TA
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (33) : 19852 - 19859
[4] Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway
Desany, BA
Alcasabas, AA
Bachant, JB
Elledge, SJ
[J]. GENES & DEVELOPMENT, 1998, 12 (18) : 2956 - 2970
[5] The Cdc7/Dbf4 protein kinase: target of the S phase checkpoint?
Jares, P
Donaldson, A
Blow, JJ
[J]. EMBO REPORTS, 2000, 1 (04) : 319 - 322
[6] The DNA replication checkpoint response stabilizes stalled replication forks
Lopes, M
Cotta-Ramusino, C
Pellicioli, A
Liberi, G
Plevani, P
Muzi-Falconi, M
Newlon, CS
Foiani, M
[J]. NATURE, 2001, 412 (6846) : 557 - 561
[7] MESELSON M, 1958, P NATL ACAD SCI USA, V64, P1242
[8] A CHECKPOINT REGULATES THE RATE OF PROGRESSION THROUGH S-PHASE IN SACCHAROMYCES-CEREVISIAE IN RESPONSE TO DNA-DAMAGE
PAULOVICH, AG
HARTWELL, LH
[J]. CELL, 1995, 82 (05) : 841 - 847
[9] Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
Pellicioli, A
Lucca, C
Liberi, G
Marini, F
Lopes, M
Plevani, P
Romano, A
Di Fiore, PP
Foiani, M
[J]. EMBO JOURNAL, 1999, 18 (22) : 6561 - 6572
[10] Rothstein R, 2000, GENE DEV, V14, P1

← 1 2 →