Retinopathy in Youth With Type 2 Diabetes Participating in the TODAY Clinical Trial

被引：98

作者：

Levitsky, Lynne L. ^{[1
]}

Danis, Ronald P. ^{[2
]}

Drews, Kimberly L. ^{[3
]}

Tamborlane, William V. ^{[4
]}

Haymond, Morey W. ^{[5
]}

Laffel, Lori

Lipman, Terri H. ^{[6
]}

机构：

[1] Massachusetts Gen Hosp, Boston, MA 02114 USA

[2] Univ Wisconsin, Madison, WI 53706 USA

[3] George Washington Univ, Washington, DC 20052 USA

[4] Yale Univ, Sch Med, New Haven, CT 06520 USA

[5] Baylor Coll Med, Houston, TX 77030 USA

[6] Childrens Hosp Philadelphia, Philadelphia, PA USA

来源：

DIABETES CARE | 2013年 / 36卷 / 06期

基金：

美国国家卫生研究院;

关键词：

PREVALENCE; COHORT; COMPLICATIONS; ADOLESCENTS; PROGRAM;

D O I：

10.2337/dc12-2387

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

OBJECTIVE-To determine the prevalence of retinopathy in 517 youth with type 2 diabetes of 2-8 years duration enrolled in the TODAY study. RESEARCH DESIGN AND METHODS-Retinal photographs were graded centrally for retinopathy using established standards. RESULTS-Retinopathy was identified in 13.7% of subjects. Prevalence increased with age, diabetes duration, and mean HbA(1c). Subjects in the highest BMI tertile had the lowest prevalence of retinopathy. CONCLUSIONS-Prevalence of retinopathy and its association with HbA(1c) and diabetes duration is similar to that previously reported in youth with type 1 diabetes and in adults with type 2 diabetes of known duration. The mechanism underlying the reduced risk of retinopathy in the most obese individuals is unknown. Follow-up of this cohort will help define the natural history of retinopathy in youth with type 2 diabetes.

引用

页码：1772 / 1774

页数：3

共 13 条

[1] C-peptide and the risk for incident complications and mortality in type 2 diabetic patients: a retrospective cohort study after a 14-year follow-up [J].