Heme oxygenase-1 and transplantation tolerance

被引：29

作者：

Bach, Fritz H. ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Beth Israel Deaconess Med Ctr, Dept Surg,Immunobiol Res Ctr, Boston, MA 02115 USA

来源：

HUMAN IMMUNOLOGY | 2006年 / 67卷 / 06期

关键词：

D O I：

10.1016/j.humimm.2006.03.006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Tolerance is the ultimate goal of transplantation: the lack of any need for immunosuppression with long-term survival of the transplanted tissue and a full immunological response to all antigens other than those on the transplant. In honor of my dear friend and colleague, Prof. Dr. Jon van Rood, I summarize here our work in this area making use of heme oxygenase-1 (HO-1) and the products that degradation of heme by HO-1 generates.

引用

页码：430 / 432

页数：3

共 6 条

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[2] Heme oxygenase-1 expression inhibits dendritic cell maturation and proinflammatory function but conserves IL-10 expression [J].

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McDaid, J ;

Yamashita, K ;

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Öllinger, R ;

Strom, TB ;

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Bach, FH ;

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FASEB JOURNAL, 2005, 19 (01) :458-+

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Otterbein, LE ;

Soares, MP ;

Yamashita, K ;

Bach, FH .

TRENDS IN IMMUNOLOGY, 2003, 24 (08) :449-455

[5] Biliverdin, a natural product of heme catabolism, induces tolerance to cardiac allografts [J].

Yamashita, K ;

McDaid, J ;

Öllinger, R ;

Tsui, TY ;

Berberat, PO ;

Usheva, A ;

Csizmadia, E ;

Smith, RN ;

Soares, MP ;

Bach, FH .

FASEB JOURNAL, 2004, 18 (02) :765-+

[6]

YAMASHITA K, IN PRESS FASEB J

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