Reversible posterior leukoencephalopathy syndrome: a possible manifestation of Wegener's granulomatosis-mediated endothelial injury

被引：14

作者：

Nishio, Minako ^{[1
]}

Yoshioka, Katsunobu ^{[1
]}

Yamagami, Keiko ^{[1
]}

Morikawa, Takashi ^{[1
]}

Konishi, Yoshio ^{[1
]}

Hayashi, Noriko ^{[2
]}

Himuro, Kimihide ^{[2
]}

Imanishi, Masahito ^{[1
]}

机构：

[1] Osaka City Gen Hosp, Dept Internal Med, Miyakojima Ku, Osaka 5340021, Japan

[2] Osaka City Gen Hosp, Dept Neurol, Miyakojima Ku, Osaka 5340021, Japan

来源：

MODERN RHEUMATOLOGY | 2008年 / 18卷 / 03期

关键词：

Reversible posterior leukoencephalopathy syndrome (RPLS); Vasculitis; Wegener's granulomatosis;

D O I：

10.1007/s10165-008-0052-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We present the case of a 15-year-old girl who had Wegener's granulomatosis with severe intestinal involvement. During the clinical course, she developed generalized seizures and was diagnosed with reversible posterior leukoencephalopathy syndrome (RPLS). Plasma exchange combined with steroid pulse therapy was initiated and showed marked improvement. This is one of the few cases of RPLS without severe hypertension or renal failure, suggesting that RPLS is likely to be a manifestation of Wegener's granulomatosis-mediated endothelial injury.

引用

页码：309 / 314

页数：6

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