Efficacy of desmopressin as surgical prophylaxis in patients with acquired von Willebrand disease undergoing thyroid surgery

被引：24

作者：

Franchini, M

De Gironcoli, M

Lippi, G

Manzato, F

Brazzarola, P

Bottura, D

Aprili, G

Gandini, G

机构：

[1] Azienda Osped Verona, Ctr Emofilia, Dipartimento Chirurg, Verona, Italy

[2] Azienda Osped Verona, Ist Chim & Microscopia Clin, Serv Immunoematol & Trasfus, Verona, Italy

[3] Univ Verona, I-37100 Verona, Italy

来源：

HAEMOPHILIA | 2002年 / 8卷 / 02期

关键词：

bleeding disorders; desmopressin; thyroid disease; von Willebrand disease;

D O I：

10.1046/j.1365-2516.2002.00589.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Coagulation abnormalities may occur in patients with thyroid diseases. We report on 14 patients undergoing thyroid surgery for a thyroid disease with an alteration of coagulation parameters resembling von Willebrand disease. Subcutaneous desmopressin was first tested and then used successfully in these patients as surgical prophylaxis, with no side-effects or bleeding complications during or after surgery. This study highlights the need for coagulation studies in patients with thyroid diseases undergoing thyroid surgery. Subcutaneous desmopressin may be used in these patients in order to prevent a surgically related bleeding risk.

引用

页码：142 / 144

页数：3

共 13 条

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