The genetics of cognitive processes: Candidate genes in humans and animals

被引：41

作者：

Morley, KI ^{[1
]}

Montgomery, GW ^{[1
]}

机构：

[1] Queensland Inst Med Res, Genet Epidemiol Lab, Brisbane, Qld 4006, Australia

来源：

BEHAVIOR GENETICS | 2001年 / 31卷 / 06期

关键词：

cognition; genetics; human; mouse; Drosophila melanogaster;

D O I：

10.1023/A:1013337209957

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

It has been hypothesized that numerous genes contribute to individual variation in human cognition. An extensive search of the scientific literature was undertaken to identify candidate genes which might contribute to this complex trait. A list of over 150 candidate genes that may influence some aspect of cognition was compiled. Some genes are particularly strong candidates based on evidence for involvement in cognitive processes in humans, mice, and Drosophila melanogaster. This survey confirms that many genes are associated with cognitive variation and highlights the potential importance of animal models in the study of human cognition.

引用

页码：511 / 531

页数：21

共 216 条

[1] Genetic demonstration of a role for PKA in the late phase of LTP and in hippocampus-based long-term memory [J].

Abel, T ;

Nguyen, PV ;

Barad, M ;

Deuel, TAS ;

Kandel, ER .

CELL, 1997, 88 (05) :615-626

[2] PKC-GAMMA MUTANT MICE EXHIBIT MILD DEFICITS IN SPATIAL AND CONTEXTUAL LEARNING [J].

ABELIOVICH, A ;

PAYLOR, R ;

CHEN, C ;

KIM, JJ ;

WEHNER, JM ;

TONEGAWA, S .

CELL, 1993, 75 (07) :1263-1271

[3] A new inherited interstitial deletion of the distal long arm of chromosome 4,{del(4)(q32 q33)} [J].

Aladhami, SMS ;

Gould, CP ;

Muhammad, FA .

HUMAN HEREDITY, 2000, 50 (02) :146-150

[4] Relation of age and apolipoprotein E to cognitive function in Down syndrome adults [J].

Alexander, GE ;

Saunders, AM ;

Szczepanik, J ;

Strassburger, TL ;

Pietrini, P ;

Dani, A ;

Furey, ML ;

Mentis, MJ ;

Roses, AD ;

Rapoport, SI ;

Schapiro, MB .

NEUROREPORT, 1997, 8 (08) :1835-1840

[5] WATSON SYNDROME - IS IT A SUBTYPE OF TYPE-1 NEUROFIBROMATOSIS [J].

ALLANSON, JE ;

UPADHYAYA, M ;

WATSON, GH ;

PARTINGTON, M ;

MACKENZIE, A ;

LAHEY, D ;

MACLEOD, H ;

SARFARAZI, M ;

BROADHEAD, W ;

HARPER, PS ;

HUSON, SM .

JOURNAL OF MEDICAL GENETICS, 1991, 28 (11) :752-756

[6] PAK3 mutation in nonsyndromic X-linked mental retardation [J].

Allen, KM ;

Gleeson, JG ;

Bagrodia, S ;

Partington, MW ;

MacMillan, JC ;

Cerione, RA ;

Mulley, JC ;

Walsh, CA .

NATURE GENETICS, 1998, 20 (01) :25-30

[7] Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 [J].

Amir, RE ;

Van den Veyver, IB ;

Wan, M ;

Tran, CQ ;

Francke, U ;

Zoghbi, HY .

NATURE GENETICS, 1999, 23 (02) :185-188

[8] The deletion allele of the angiotensin I converting enzyme gene as a genetic susceptibility factor for cognitive impairment [J].

Amouyel, P ;

Richard, F ;

Cottel, D ;

Amant, C ;

Codron, V ;

Helbecque, N .

NEUROSCIENCE LETTERS, 1996, 217 (2-3) :203-205

[9] Behavioral alterations associated with apoptosis and down-regulation of presenilin 1 in the brains of p53-deficient mice [J].

Amson, R ;

Lassalle, JM ;

Halley, H ;

Prieur, S ;

Lethrosne, F ;

Roperch, JP ;

Israeli, D ;

Gendron, MC ;

Duyckaerts, C ;

Checler, F ;

Dausset, J ;

Cohen, D ;

Oren, M ;

Telerman, A .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (10) :5346-5350

[10]

ASZTALOS Z, 1993, J NEUROSCI, V13, P924

← 1 2 3 4 5 6 7 8 9 10 →