Comparative Population Analysis of Klebsiella pneumoniae Strains with Extended-Spectrum β-Lactamases Colonizing Patients in Rehabilitation Centers in Four Countries

被引:46
作者
Baraniak, A. [1 ]
Izdebski, R. [1 ]
Fiett, J. [1 ]
Sadowy, E. [1 ]
Adler, A. [2 ]
Kazma, M. [2 ]
Salomon, J. [3 ]
Lawrence, C. [4 ]
Rossini, A. [5 ]
Salvia, A. [5 ]
Vidal Samso, J. [6 ]
Fierro, J. [6 ]
Paul, M. [7 ]
Lerman, Y. [8 ]
Malhotra-Kumar, S. [9 ]
Lammens, C. [9 ]
Goossens, H. [9 ]
Hryniewicz, W. [1 ]
Brun-Buisson, C. [10 ,11 ]
Carmeli, Y. [2 ]
Gniadkowski, M. [1 ]
机构
[1] Natl Med Inst, Warsaw, Poland
[2] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Div Epidemiol & Prevent Med, IL-69978 Tel Aviv, Israel
[3] Cnam, MSRSS, INSERM, Paris, France
[4] Univ Paris Ile France Ouest, Grp Hosp, Paris, France
[5] Fdn Santa Lucia IRCCS, Rome, Italy
[6] Inst Guttmann, Barcelona, Spain
[7] Loewenstein Hosp & Rehabil Ctr, Raanana, Israel
[8] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Div Geriatr, IL-69978 Tel Aviv, Israel
[9] Univ Antwerp, B-2020 Antwerp, Belgium
[10] Hop Henri Mondor, INSERM, U957, F-94010 Creteil, France
[11] Univ Paris Est, Creteil, France
关键词
AMPC-TYPE CEPHALOSPORINASES; FIELD GEL-ELECTROPHORESIS; MOLECULAR EPIDEMIOLOGY; SEQUENCE TYPES; CTX-M; DISSEMINATION; ENTEROBACTERIACEAE; CLONES; ST11; RESISTANCE;
D O I
10.1128/AAC.02571-12
中图分类号
Q93 [微生物学];
学科分类号
071005 [微生物学];
摘要
The international project MOSAR was conducted in five rehabilitation centers; patients were screened for rectal carriage of extended-spectrum beta-lactamase (ESBL)-producing members of the Enterobacteriaceae. Among 229 Klebsiella pneumoniae isolates, four clonal groups (CG) or complexes (CC) prevailed: CG17 in France, CG101 in Italy, CG15 in Spain, and CC147 in Israel. ESBLs, mainly CTX-Ms, were produced by 226 isolates; three isolates expressed AmpC-like cephalosporinases. High genetic diversity of K. pneumoniae populations was observed, with specific characteristics at each center.
引用
收藏
页码:1992 / 1997
页数:6
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