Comorbidity of Allergic and Autoimmune Diseases Among Patients With ADHD: A Nationwide Population-Based Study

被引：75

作者：

Chen, Mu-Hong ^{[1
]}

Su, Tung-Ping ^{[1
,2
]}

Chen, Ying-Sheue ^{[1
]}

Hsu, Ju-Wei ^{[1
]}

Huang, Kai-Lin ^{[1
,2
]}

Chang, Wen-Han ^{[1
]}

Chen, Tzeng-Ji ^{[3
,4
]}

Bai, Ya-Mei ^{[1
,2
]}

机构：

[1] Taipei Vet Gen Hosp, Dept Psychiat, Taipei, Taiwan

[2] Natl Yang Ming Univ, Dept Psychiat, Coll Med, Taipei, Taiwan

[3] Taipei Vet Gen Hosp, Dept Family Med, Taipei, Taiwan

[4] Natl Yang Ming Univ, Inst Hosp & Hlth Care Adm, Taipei, Taiwan

来源：

JOURNAL OF ATTENTION DISORDERS | 2017年 / 21卷 / 03期

关键词：

ADHD; allergy; autoimmune diseases; comorbidity; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT HYPERACTIVITY DISORDER; INFLAMMATORY-BOWEL-DISEASE; THYROID-FUNCTION; HLA-DR; PSYCHIATRIC COMORBIDITY; MENTAL-DISORDERS; CHILDHOOD ASTHMA; ATOPIC ECZEMA; ASSOCIATION;

D O I：

10.1177/1087054712474686

中图分类号：

B844 [发展心理学（人类心理学）];

学科分类号：

040206 [发展心理学];

摘要：

Objective: Patients with ADHD have been suggested to have increased risks of allergic diseases but without consistent results, and limited studies about the association between ADHD and autoimmune diseases were noted in the literature. Method: Utilizing the Taiwan National Health Insurance Research Database, ADHD patients were identified and compared with age- and gender-matched controls (1:4). Results: In all, 8,201 participants were identified as having ADHD, and an increased prevalence of allergic diseases, including asthma (odds ratio [OR] = 1.53), allergic rhinitis (OR = 1.59), atopic dermatitis (OR = 1.53), and urticaria (OR = 1.39), compared with the control group. Although the comorbidity of autoimmune diseases with ADHD was low, ADHD patients had a significantly greater prevalence of ankylosing spondylitis (OR = 2.78), ulcerative colitis (OR = 2.31), and autoimmune thyroid disease (OR = 2.53) than the controls. Conclusion: Our results supported the association between ADHD and allergic/autoimmune diseases. The further studies will be required to clarify the underlying mechanisms.

引用

页码：219 / 227

页数：9

共 68 条

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