Synthesis and biological activity of some new pyrazolo[3,4-b]pyrazines

被引：45

作者：

El-Emary, TI ^{[1
]}

机构：

[1] Assiut Univ, Fac Sci, Dept Chem, Assiut 71516, Egypt

来源：

JOURNAL OF THE CHINESE CHEMICAL SOCIETY | 2006年 / 53卷 / 02期

关键词：

pyrazolo[3,4-b]pyrazines; pyrazine; pyrazole; antifungal and antibacterial activities;

D O I：

10.1002/jccs.200600050

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

New derivatives of pyrazolo[3,4-b]pyrazine and related heterocycles were prepared starting from 6-amino-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyrazine-5-carbonitrile (2) and using the key intermediates 4, 5, 6, 14, 15 and 16. Some of the prepared compounds were evaluated for their antifungal and antibacterial activities.

引用

页码：391 / 401

页数：11

共 17 条

[1]

Studies with polyfunctionally substituted heterocycles:: New synthesis of pyrido[5′,4′:2,3][1,3,4]oxadiazolo[3,2-a]pyridine; pyridazine; 1,3,4-oxadiazole; and Pyrazolo[1,5-a]pyrimidine derivatives [J].