The kinetics of skin thinning induced by topical fluticasone propionate 0.05% cream in volunteer subjects

被引：9

作者：

Dykes, PJ ^{[1
]}

Marks, R ^{[1
]}

Hill, S ^{[1
]}

Mills, C ^{[1
]}

Eastwood, R ^{[1
]}

机构：

[1] GLAXO LABS LTD,UXBRIDGE,MIDDX,ENGLAND

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 1996年 / 21卷 / 03期

关键词：

D O I：

10.1111/j.1365-2230.1996.tb00058.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Fluticasone propionate (FP) 0.05% (Cutivate(TM)) cream is a novel corticosteroid used for the treatment of corticosteroid-responsive dermatoses. To date there are no published data concerning its effect on cutaneous atrophy. This randomized, double-blind study of 40 volunteer subjects was performed to investigate the kinetics of skin thinning induced by topical 0.05% FP cream vs. placebo after once-daily application for 2-8 weeks. The results of this study showed no significant effect on the skin thickness of subjects after 8 weeks' treatment with 0.05% FP cream compared with placebo.

引用

页码：180 / 184

页数：5

共 13 条

[1] DETERMINING SKIN THICKNESS WITH PULSED ULTRA SOUND [J].