Morphogenesis of Escherichia coli

被引:75
作者
Vollmer, W [1 ]
Höltje, JV [1 ]
机构
[1] Max Planck Inst Entwicklungsbiol, Biochem Abt, D-72076 Tubingen, Germany
关键词
D O I
10.1016/S1369-5274(01)00261-2
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Morphogenesis of the rod-shaped Escherichia coli is determined by controlled growth of an exoskeleton made of murein (peptidoglycan). Recent insights in the growth strategy of the stress-bearing murein sacculus has contributed to our understanding of how the required concerted action of murein polymerizing and hydrolyzing enzymes is achieved. The proteins involved are coordinated by the formation of multienzyme complexes. In this review, we summarize the recent results on murein structure and metabolism. On the basis of these findings, we present a model that explains maintenance of the specific rod shape of E. coli.
引用
收藏
页码:625 / 633
页数:9
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