Codon 72 polymorphism of p53 and its association with cervical cancer

被引:127
作者
Zehbe, I [1 ]
Voglino, G
Wilander, E
Genta, F
Tommasino, M
机构
[1] Deutsch Krebsforschungszentrum, D-69120 Heidelberg, Germany
[2] Osped St Anna, Serv Anat Patol, I-10126 Turin, Italy
[3] Univ Uppsala Hosp, Dept Genet & Pathol, S-75185 Uppsala, Sweden
关键词
D O I
10.1016/S0140-6736(99)01914-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Swedish and Italian women with HPV is-positive cervical disease were checked for codon 72 polymorphisms of p53. In both groups, arginine homozygotes were enriched in cancer compared with controls and precursor lesions.
引用
收藏
页码:218 / 219
页数:2
相关论文
共 5 条
  • [1] Homozygous arginine-72 in wild type p53 and risk of cervical cancer
    Hayes, VM
    Hofstra, RMW
    Buys, CHCM
    Hollema, H
    van der Zee, AGJ
    [J]. LANCET, 1998, 352 (9142) : 1756 - 1756
  • [2] Josefsson AM, 1998, NATURE, V396, P531, DOI 10.1038/25037
  • [3] p53 polymorphism and risk of cervical cancer
    Lanham, S
    Campbell, I
    Watt, P
    Gornall, R
    [J]. LANCET, 1998, 352 (9140) : 1631 - 1631
  • [4] p53 codon 72 polymorphism and risk of cervical cancer in UK
    Rosenthal, AN
    Ryan, A
    Al-Jehani, RM
    Storey, A
    Harwood, CA
    Jacobs, IJ
    [J]. LANCET, 1998, 352 (9131) : 871 - 872
  • [5] Role of a p53 polymorphism in the development of human papillomavirus-associated cancer
    Storey, A
    Thomas, M
    Kalita, A
    Harwood, C
    Gardiol, D
    Mantovani, F
    Breuer, J
    Leigh, IM
    Matlashewski, G
    Banks, L
    [J]. NATURE, 1998, 393 (6682) : 229 - 234